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Curodont Repair Fluoride Plus

CurodontTM Repair
Fluoride Plus

Treats early caries in less than 3 minutes via Guided Hydroxyapatite Generation* throughout the depth of the lesion.

  • Non-invasive, drill-free application
  • Fast & easy to apply in as little as 3 minutes (same appointment)**
  • Works on all surfaces: smooth, interproximal, occlusal enamel surfaces, demineralized white spots
  • Can be applied by trained clinicians, including hygienists***
  • Non-staining & tasteless
  • Suitable for all ages****
  • New & improved design

Now easier and faster to use!

Contact us for more information

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Description

Contains 10 units A and 10 units B
10 x 0.0085 fl. oz. (10 x 0.25 ml)

USE
Professional product, for in-office use only.

Sodium Fluoride, Water, Chlorhexidine diglucconate, Tromethamine, Trehalose Dihydrate, Oligopeptide-104, Hydroxypropyl Methylcellulose

USE
In office

ORDER WITH YOUR LOCAL DISTRIBUTOR
Availability expected by end of September – distributor dependent

Midwest Dental

What’s New & Improved

NEW PACKAGING

UNIT A: 10 blisters with one sponge each

UNIT B: 2 pouches with five droppers each


Instructions Card

IMPROVED APPLICATION

Precise targeted application with new sponge

Improved access, more maneuverability and tactile feedback

 


Use your cotton pliers or another suitable instrument to pick up the  sponge

OPTIMIZED PROTOCOL

No waiting time

In as little as 3 minutes


Ease of workflow integration

Mode of Action

IN-DEPTH TREATMENT

Guided Hydroxyapatite Generation* throughout the depth of the lesion

Our proprietary biomimetic formulation disperses throughout the depth of the lesion.

Mimicking nature, Curodont treats the early-stage carious lesions by restoring lost minerals together with calcium and phosphate from saliva.

This allows for the opportunity to preserve the natural tooth structure – without the need for drilling, injections, or artificial filling materials.

*Also referred to as Guided Enamel Repair

1. Natural caries protection In a healthy oral environment, saliva facilitates constant remineralization. Saliva is rich in calcium and phosphate. Fluoride actively supports this natural remineralization process and strengthens enamel.
2. Increased risk of caries The constant acid challenge from bacteria inhibits the natural remineralization cycle and tooth minerals are lost. If demineralization cannot be stopped, enamel becomes porous (i.e. white spots). Targeted anti-caries measures are needed.
3. CurodontTM Repair Fluoride Plus applied directly onto the cleaned surface of the white spot CurodontTM Repair Fluoride Plus acts where it is needed. Over the course of the weeks the application procedure help minerals, like fluoride and calcium, to penetrate the enamel surface into the white spots and to remineralize and re-harden the affected enamel over the next few weeks.

Visible Evidence - Case Studies

Interproximal early carious lesion in the aesthetic zone
50-year-old male patient


Courtesy: Dr. Gavin Miller

White spot lesions during fixed orthodontic therapy
10-year-old female patient

Courtesy: Misty Mattingly, RDH

Interproximal early carious lesion interpreted with AI
50-year-old male patient

Courtesy: Dr. Rebecca Pounds

These results may not be typical. Individual results may vary.

GO TO CASE GALLERY

Scientific Evidence

A recent in vitro study (n=3) evaluated the effect of treating early caries lesions with one application of CurodontTM 
and demonstrated hydroxyapatite generation throughout the depth of the lesion within as little as 2 weeks

SEM (Scanning Electron Microscope)​

Negative control
Untreated enamel shows no evidence of structural repair
2 weeks after the one-time application of CurodontTM
Enamel treated with CurodontTM shows hydroxyapatite generation throughout the lesion.

Micro CT Evidence

A statistically significant average increase of 15% in mineral density throughout the lesion was observed within only 2 weeks (p<0.001)***, independently of the lesion depth

An exemplary depth profile up to 90% of the initial lesion.
Depth was measured at 20um, 50um and full depth (100um).
In all cases, a statistically significant increase in mineral density seen throughout the lesion.

***The p-value is calculated based on averages and standard deviations which allows to draw a conclusion on statistical significance.

Data on file (2025), vVARDIS funded in vitro study

READ THE FULL ARTICLE

Expected Benefits

For Patients

  • Drill- and needle-free treatment
  • Repairs enamel over time without artificial filling materials
  • Helps to maintain healthy tooth structure
  • Can be performed in the same appointment

For Practices

  • 3-minute treatment, same appointment
  • Easy integration into all existing workflows
  • Helps optimize use of chair time 
  • Additional service to grow your practice
  • Helps increase patient word of mouth

How to Apply

PRODUCT PREPARATION​

Carefully peel the cover off UNIT A to expose the sponge.
Retrieve one UNIT B dropper.
Put the remaining unopened dropper(s) back in the pouch.
Immerse the sponge fully with UNIT B liquid* and let it soak for at least 2 minutes. Do not replace UNIT B with any other liquid.
*Minimal liquid left over in the dropper inadvertently is acceptable.

PATIENT PREPARATION

While the sponge is soaking proceed with preparing the treatment site:
  • Clean the treatment site using one of your preferred methods, i.e.:
    • Pumice
    • Prophy paste (with or without fluoride)
    • Air Polisher
  • Rinse and dry.
  • Etch using 35 % phosphoric acid for not more than 20 seconds. Rinse and dry.
  • Once the sponge is fully saturated and soft, place cotton rolls around the treatment site.

APPLICATION

Use cotton pliers/hemostat to pick up the soft saturated sponge.

For interproximal application, apply from the lingual embrasure followed by the buccal embrasure.

No need to use separators or a wedge 
  • Instruct the patient not to eat, drink, or rinse for 30 minutes after application.
  • Provide routine oral hygiene instructions.
  • Discharge.
  • Dispose the used sponge and dropper.
DOWNLOAD INSTRUCTIONS FOR USE
APPLICATION TIPS
  • Hold the sponge firmly from one of its corners, as you would a cotton pellet.
  • Use floss to apply prophy paste/pumice on interproximal surfaces, if needed.
  • Unwaxed floss must be used to apply etch for interproximal surfaces.
  • No need to use separators or a wedge (sponge doesn’t have to touch the lesion).
  • Simply squeeze the sponge on the lesion, if interproximal apply from buccal and lingual sides.
  • The liquid will quickly be absorbed on the etched enamel surface through capillary action.
  • Any minor bleeding while preparing the treatment site should be controlled before proceeding with applying CurodontTM Repair Fluoride Plus on the lesion.
Download curodontTM repair fluoride plus workflow
Application on Interproximal Surfaces

Video

Application on Smooth Surfaces

Video

Application around Orthodontic Brackets

Video

Application on Occlusal Surfaces

Video

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INFORMATION REQUEST

How to Apply (Previous Generation)

The non-invasive therapy with CURODONTTM REPAIR FLUORIDE PLUS (CRFP) is as safe as its application is easy. The entire process of applying CRFP is completed within 8-10 minutes, without drilling, anesthesia, or pain.

 

PREPARATION

  1. Remove pellicle using your preferred method (i.e. pumice, prophy paste, air polisher or 2% sodium hypochlorite).​​
  2. Rinse and dry.
  3. Etch using 35% phosphoric acid for 20 seconds. Follow with unwaxed dental floss on interproximal sites.​​
  4. Rinse and dry.​
  5. Basic isolation of the treatment area (cotton rolls, dry aids, etc.) No rubber dam necessary. ​​
  6. Proceed with the application of CURODONT™ REPAIR FLUORIDE PLUS, as per instructions below.
    ​

APPLICATION

7. Remove safety clip (black).
8. Activate the CURODONT™ REPAIR FLUORIDE PLUS applicator by pushing the two cylinders together so that the liquid flows into the sponge. Wait 10 seconds until the sponge is saturated.​
9. Remove the CURODONT™ REPAIR FLUORIDE PLUS applicator from the protective cover. The sponge applicator and liquid must be used together.
10. Apply CURODONT™ REPAIR FLUORIDE PLUS by squeezing the sponge on the lesion. If interproximal apply from buccal and lingual sides, the use of separators or wedges are not needed. ​
11. Wait for 5 minutes. Do not rinse.​
12. Instruct patient not to rinse, eat or drink for 30 minutes. The applicator is for single patient use only! Discard the applicator unit after use​.

Testimonials

“With the new applicator design, Curodont has become a “Grab and Go” protocol. Grabbing the sponge with the tweezer feels so natural. When pressing on the treatment site, I can feel the sponge and clearly see the formulation coming out. I am instantaneously confident that I treated the early lesion appropriately. There is no need any more to let it sit for 5min with the patient mouth opened. I can just go and treat the next patient while my team provides at home instructions. This is a game changer for Curodont. It will boost adoption."
Dr. Leonard M BadgerDDS
“This new applicator design and protocol will allow us to be more confident and efficient. The tactile feedback of the sponge feels so good. Integrating Curodont into our typical appointment will be much easier. Prepping and applying will virtually add no time, especially if it is planned early in the appointment. Combined with the clinical benefits of arresting and potentially reversing early decay, Curodont is truly a no brainer!”
Sarika RambhaiRDH
“Now, we have a product that enables early intervention and the remineralization of early caries before a restoration is required.”
Robert Mongrain
Robert MongrainDMD
“Adopting minimally invasive, early interception methods is the future of dentistry and in the best interest of our patients.”
Sarah Eller
Sarah EllerRDH, IPDH
“The really cool part I love about CurodontTM, it really gives the hygienist a new opportunity and really expands their scope of practice in a way. "
Misty Mattingly
Misty MattinglyRDH
“Join the revolution in dental care, say goodbye to the old ways of fearing the dentist and hello to a brighter healthier smile with vVARDIS CurodontTM Repair Fluoride Plus.”
Misty Mattingly
Misty MattinglyRDH
“My patients are excited about the idea of no needle or drilling in addition to preventing the long-term maintenance a restoration requires. I am pleased that we’ve been able to educate patients on early caries intervention”
Sarah EllerRDH, IPDH
“Having CurodontTM Repair Fluoride Plus in my toolkit empowers me to offer more individualized care and better meet the needs of my patients. It expands your options to better serve your patient population and provide comprehensive patient care.”
Jeanette MacLean
“Offering CurodontTM is only going to help your practice grow, so why would you just watch something in this day and age when you can do something? If we have a treatment option that can help prevent incipient lesions from reaching the point of no return and extend the lifetime of patients’ natural dentition, that is very advantageous”
Jeanette MacLean
“I have been waiting my whole career to become a medical dental doctor, to get to the root cause. This formulation product to allow me to fulfil my career.”
Dr. Robert Mongrain
“I'm just so thankful for products like these, because I can do something instead of just watching and waiting. I can actually do something to help this patient.”
Crystal SpringRDH
“CurodontTM Repair Fluoride Plus is popular with patients, a large majority of whom have enthusiastically accepted treatment upon learning about the opportunity to address a non-cavitated lesion before it can worsen and possibly lead to invasive restorative treatment. ….. That’s because they like the idea of not having to be drilled on for a restoration."
Dr. William J Moorhead (‘Dr. Checklist’)DMD
“Curodont™ is highly effective for treatment of early decays. This new non-invasive therapeutic option is a game changer in the battle against tooth decay.”
Dr. German O. GallucciHarvard School of Dental Medicine
“As an epidemiologist and cariologist who has studied dental caries for over four decades and developed guidelines for its diagnosis and management, I can state without hesitation that the advent of Curodont™ represents a significant breakthrough in caries management.”
Prof. Amid I. IsmailLaura H. Carnell Professor and Dean of the Kornberg School of Dentistry, Temple University
“Curodont™ represents a transformative step forward in dentistry. At Heartland Dental, we’ve seen firsthand how this innovation empowers clinicians to treat early-stage caries non-invasively, improving outcomes and deepening patient trust. It’s not just a product – it's a shift in how we think about the future of oral health.”
Dr. Timothy QuirtDDS, MBA
“What makes Curodont™ especially impactful is its potential to reduce tooth decay among vulnerable populations—particularly children and those covered by Medicaid. Curodont™ isn’t just a new tool; it’s a meaningful, science-driven advancement that is reshaping healthcare and setting a higher standard for dentistry where it’s needed most."
Dr. Shan K. BagbyDMD, MHA, FACHE
Lou Graham, DDS
Amanda Hill, RDH & Crystal Spring, RDH
Daniel Avila, BSDH, RDH & Laura Bettencourt, BSDH, RDH
Dr. Adam Silevitch, DMD
Crystal Spring
Dr. Robert Mongrain, DMD
Dr. William Moorhead, DMD
Dr. Kelly Tanner, RDH
Interview with Anja
Dr. Justin Rashbaum
Interview with Raman
Interview with Saxer

FAQs

CURODONTTM REPAIR FLUORIDE PLUS is a locally applied formulation for the in-office management
of early, non-cavitated caries lesions (watch areas).

The proprietary formulation of CURODONTTM REPAIR FLUORIDE PLUS diffuses throughout the early carious lesion (watch area) and, together with calcium and phosphate from saliva, repairs enamel. Over time, CURODONTTM REPAIR FLUORIDE PLUS repairs the lesion, enabling preservation of the natural tooth.

CURODONTTM REPAIR FLUORIDE PLUS is a low-viscosity liquid material that can be used to repair early, non-cavitated carious lesions. These lesions often appear as white spots (and, occasionally, brown) on buccal and occlusal surfaces. For proximal lesions, which may not be visually accessible, radiographs and/or advanced diagnostic measures, such as laser fluorescence, fiber-optic transillumination, impedance measurement, etc. may be used.

CURODONTTM REPAIR FLUORIDE PLUS works on early, non-cavitated carious lesions (watch areas). Cavitated lesions, which represent an advanced stage of the carious process, must be treated with restorations that require drilling of the tooth. Detection and treatment of caries in their incipient stages with CURODONTTM REPAIR FLUORIDE PLUS can stop their progression to cavitated lesions.

CURODONTTM REPAIR FLUORIDE PLUS can be used for treatment of early, non-cavitated carious lesions on all tooth surfaces. Therefore, the range of lesions that be treated using CURODONTTM REPAIR FLUORIDE PLUS, according to popular classification systems, include:

i. E1 and E2 lesions(according to E0-E2, D1-D3 notation system). Occasionally, D1 lesions may be treated, only if they are not cavitated.
[Anusavice K. Present and future approaches for the control of caries. J Dent Educ. 2005;69(5):538-854.]

ii. D1 and D2 lesions. Occasionally, D3 lesions may be treated only if they are not cavitated
[Marthaler TM: A standardized system of recording dental conditions. Helv Odontol Acta 1966;10:1–18.]

iii. Score 1, score 2, and score 3 (according to ICDAS II scoring system).
[https://iccms-web.com/uploads/asset/592848be55d87564970232.pdf. Accessed 01/02/2022]

If the carious lesion is in the form of a microcavity (ICDAS score 3), CURODONTTM REPAIR FLUORIDE PLUS may be used, but will not fill the microcavity.
If frank cavitation is present, which means a hole has developed in the tooth due to the decay, removal of the caries and a restoration to fill the cavity is needed. CURODONTTM REPAIR FLUORIDE PLUS is not indicated for such lesions.

Caries is the most prevalent oral disease* that begins with superficial demineralization of the enamel and, if not treated, can progress and lead to irreversible loss of tooth structure. In its advanced stages, when it has progressed to the middle or inner thirds of dentin, the carious lesions may become cavitated. Once a cavity develops, the only resort is to restore it with an artificial material. Intervening when the carious lesion is still in its incipient stages could potentially prolong the life of a tooth. CURODONTTM REPAIR FLUORIDE PLUS can be used to non-invasively treat early caries and help stop progression.

* Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet 2018; 392: 1789–8583

Yes, CURODONTTM REPAIR FLUORIDE PLUS can be used in patients at high risk for developing caries. However, in such cases, a strict regimen of regular recalls and reinforcement of oral hygiene measures must be adopted.

No. The use of a rubber dam is not necessary, though it is the clinician’s decision whether to use a rubber dam. Basic aids such as cotton rolls and a saliva ejector are sufficient.

In many cases, one application of CURODONTTM REPAIR FLUORIDE PLUS is sufficient to treat one lesion.
If deemed necessary by the clinician, the application may be repeated such as in high-risk cases.

CURODONTTM REPAIR FLUORIDE PLUS, with 500 PPM of sodium fluoride as the active ingredient, has no reported side effects. It has been used on over 1 million teeth and over 400,000 teeth in the USA* with no reported adverse events. We recommend regular dental appointments to detect caries in the early stages and their non-invasive management using CURODONTTM REPAIR FLUORIDE PLUS.
*Data on file

CURODONTTM REPAIR FLUORIDE PLUS is a proprietary formula that treats early caries by Guided Enamel Repair. Sodium Fluoride is also known to be an effective remineralization agent. The speed with which the effect is seen depends on a number of patient behavioral and environmental factors, such as oral hygiene maintenance, quality of saliva, dietary habits, etc. Many patients see lack of caries progression and repair after one application.

CURODONTTM REPAIR FLUORIDE PLUS addresses early caries non-invasively through Guided Enamel Repair. In this process, the white appearance of the lesions may fade to a significant extent but might not completely disappear. Additionally, CURODONTTM REPAIR FLUORIDE PLUS is not intended to treat cosmetic white spots.

Immediately after the application of CURODONTTM REPAIR FLUORIDE PLUS, the patient should refrain from eating, drinking or rinsing for 30 minutes. Routine oral hygiene measures including brushing with fluoridated toothpaste twice a day should be followed. Additionally, and especially, in cases with early interproximal caries, interdental flossing must be performed after meals to ensure the cleanliness of the area.

Yes, CURODONTTM REPAIR FLUORIDE PLUS can be used on early caries developing around bonded brackets. Patients undergoing fixed orthodontic treatment are at an increased risk of developing caries, due to difficulty in oral hygiene maintenance. Since the use of CURODONTTM REPAIR FLUORIDE PLUS does not require the placement of a rubber dam or any finishing and polishing procedures, it can easily be used around bonded brackets.

The demineralized state of early carious lesions provides the right environment for the CURODONTTM REPAIR FLUORIDE PLUS proprietary formula to work. CURODONTTM REPAIR FLUORIDE PLUS is not indicated for use in cosmetic white spots or those that have a non-bacterial etiology.

Success with CURODONTTM REPAIR FLUORIDE PLUS is the lack of progression of a treated early carious lesion. This can be seen either as stability in the lesion size or as the reduction in the size and depth of the lesion over time. The ‘whiteness’ of carious white spot lesions may reduce but might not completely regain the appearance of sound enamel. Thus, it is important to treat these lesions with CURODONTTM REPAIR FLUORIDE PLUS as early as possible to obtain the optimal desired outcome.

While CURODONTTM REPAIR FLUORIDE PLUS is not bactericidal, its proprietary formula helps attract calcium and phosphate found in the saliva to help replace lost hydroxyapatite in the early carious lesions. These minerals are delivered to the lesion to repair early caries and help stop their progression.

DOWNLOAD FAQs

*Also referred to as Guided Enamel Repair
**Based on user evaluation with N = 30 GPs and hygienists applying product on a phantom head following protocol
*** State dependent
**** Children under 6 years of age: consult a dentist or doctor.

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