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CurodontTM Repair
Fluoride Plus

Biomimetic system for Guided Enamel Remineralization of early caries

– Professional product, for dental professionals only –

CURODONTTM REPAIR FLUORIDE PLUS is a biomimetic, brush-on system for the treatment of early carious lesions through Guided Enamel Remineralization.

Its proprietary formulation diffuses throughout the lesion to remineralize the watch area, enabling the preservation of the natural tooth.

Quick and easy application – Non-invasive – Non-staining – For all surfaces – For all patients.

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Darby Dental

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Description

Box contains 10 single packed single use applicators with 0.1 ml rinse each.

USE
In office

Sodium Fluoride, Water, Chlorhexidine diglucconate, Tromethamine, Trehalose Dihydrate, Oligopeptide-104, Hydroxypropyl Methylcellulose

USE
In office

Mode of Action

Guided Enamel Remineralization through targeted application

The proprietary formulation diffuses throughout the lesion to provide the remineralizing agent, fluoride, together with calcium and phosphate from saliva where it is needed most. ​

​Over time, Curodont Repair Fluoride Plus remineralizes the watch area, aiding in the prevention of cavity progression and enabling preservation of the natural tooth.​

​Without injections, pain or drilling.​

Play Video
1. Natural caries protection In a healthy oral environment, saliva facilitates constant remineralization. Saliva is rich in calcium and phosphate. Fluoride actively supports this natural remineralization process and strengthens enamel.
2. Increased risk of caries The constant acid challenge from bacteria inhibits the natural remineralization cycle and tooth minerals are lost. If demineralization cannot be stopped, enamel becomes porous (i.e. white spots). Targeted anti-caries measures are needed.
3. CurodontTM Repair Fluoride Plus applied directly onto the cleaned surface of the white spot CurodontTM Repair Fluoride Plus acts where it is needed. Over the course of the weeks the application procedure help minerals, like fluoride and calcium, to penetrate the enamel surface into the white spots and to remineralize and re-harden the affected enamel over the next few weeks.

Visible Evidence - Case Studies

Multiple post-orthodontic interproximal initial carious lesions
14-year-old male patient
Courtesy of Dr. Alisha Gray, Ohio, US
White spot lesions during fixed orthodontic therapy
10-year-old female patient
Courtesy of Misty Mattingly, RDH, BS, SAGE Dental, US
Proximal initial carious lesion interpreted with AI
50-year-old male patient
Courtesy of Dr. Rebecca Pounds, Pennsylvania, US
These results may not be typical. Individual results may vary.
GO TO CASE STUDIES

Expected Benefits

Helps to prevent
the progression of the
‘watch area’
Remineralizes over time
Patient dependent, linked to multiple risk factors
Helps maintain natural tooth structure

Visible Evidence

Remineralisation of a proximal caries lesion
Dr. Markus Schlee: Stomatologie 2014 (111); 175 – 181
Day 0
After six months
Occlusal caries
Dr. Frank Bröseler, 2012
Day 0
After six months
Visible “fading“ of the white spot lesion
Dr. Frank Bröseler: Broeseler, F. Et al. Clin Oral Invest 2020; 24: 123 – 132
Day 0
After six months

Science

  • 10+ years in clinical practice
  • Over 100,000 successfully treated patients, with no side effects
  • More than 20 years of research
  • > 230 scientific peer-reviewed literature
Literature

Guided Enamel Remineralization

Guided Enamel Remineralization (GER) tackles initial carious lesions. GER bridges the gap between prevention and invasive restorative approaches. It enables effective therapy of initial caries and white spots through in-depth remineralization of the enamel, while still maintaining the integrity of the tooth.

How to apply

The non-invasive therapy with CURODONTTM REPAIR FLUORIDE PLUS (CRFP) is as safe as its application is easy. The entire process of applying CRFP is completed within 8-10 minutes, without drilling, anesthesia, or pain.

 

PREPARATION

  1. Remove pellicle using your preferred method (i.e. pumice, prophy paste, air polisher or 2% sodium hypochlorite).​​
  2. Rinse and dry.
  3. Etch using 35% phosphoric acid for 20 seconds. Follow with unwaxed dental floss on interproximal sites.​​
  4. Rinse and dry.​
  5. Basic isolation of the treatment area (cotton rolls, dry aids, etc.) No rubber dam necessary. ​​
  6. Proceed with the application of CURODONT™ REPAIR FLUORIDE PLUS, as per instructions below.
    ​

APPLICATION

7. Remove safety clip (black).
8. Activate the CURODONT™ REPAIR FLUORIDE PLUS applicator by pushing the two cylinders together so that the liquid flows into the sponge. Wait 10 seconds until the sponge is saturated.​
9. Remove the CURODONT™ REPAIR FLUORIDE PLUS applicator from the protective cover. The sponge applicator and liquid must be used together.
10. Apply CURODONT™ REPAIR FLUORIDE PLUS by squeezing the sponge on the lesion. If interproximal apply from buccal and lingual sides, the use of separators or wedges are not needed. ​
11. Wait for 5 minutes. Do not rinse.​
12. Instruct patient not to rinse, eat or drink for 30 minutes. The applicator is for single patient use only! Discard the applicator unit after use​.
Play Video
Download curodontTM repair fluoride plus workflow

For caries classification, please visit ADA or FDI

Smooth Surface

Application Video

Interproximal Surface

Application Video

Occlusal Surface

Application Video

Ortho Case

Application Video

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INFORMATION REQUEST

FAQ

Curodont Repair Fluoride Plus is a locally applied formulation for the in-office management of early, non-cavitated caries (watch areas/white spot lesions).

Curodont Repair Fluoride Plus’s proprietary formula diffuses throughout the early carious lesion through capillary action and over time helps attract calcium and phosphate ions found in the saliva to help remineralize the tooth.

Curodont Repair Fluoride Plus is a low-viscosity liquid material that can be used to arrest the progression and enable regression of non-cavitated carious lesions (watch areas/white spot lesions) through remineralization. These lesions often appear as white spots on buccal and occlusal surfaces. For proximal lesions, which may not be visually accessible, radiographs and/or advanced diagnostic measures, such as laser fluorescence, fiber-optic transillumination, impedance measurement, etc. may be used.

Curodont Repair Fluoride Plus works on early, non-cavitated carious lesions (watch areas/white spot lesions). Cavitated lesions, which represent an advanced stage of the carious process, must be treated with restorations that require drilling of the tooth. Detection and treatment of caries in their incipient stages with Curodont Repair Fluoride Plus can prevent or delay their progression to cavitated lesions.

Curodont Repair Fluoride Plus can be used for treatment of early, non-cavitated carious lesions (watch areas/white spot lesions) on all tooth surfaces. Therefore, the range of lesions that be treated using Curodont Repair Fluoride Plus, according to popular classification systems, include:

i. E1, E2, and D1 carious lesions (according to E0-E2, D1-D3 notation system). D1 lesions treated only if they are not cavitated.
[Anusavice K. Present and future approaches for the control of caries. J Dent Educ. 2005;69(5):538-854.]

ii. D1, D2, and D3 lesions. D3 lesions only if they are not cavitated
[Marthaler TM: A standardized system of recording dental conditions. Helv Odontol Acta 1966;10:1–18.]

iii. Score 1, score 2, and score 3 (according to ICDAS II scoring system)
[https://iccms-web.com/uploads/asset/592848be55d87564970232.pdf. Accessed 01/02/2022]

If the carious lesion is in the form of a microcavity (ICDAS score 3), Curodont Repair Fluoride Plus may be used, but will not fill the microcavity.
If frank cavitation is present, which means a hole has developed in the tooth due to the decay, removal of the caries and a restoration to fill the cavity is needed. Curodont Repair Fluoride Plus is not indicated for such lesions.

Caries is the most prevalent oral disease* that begins with superficial demineralization of the enamel and, if not treated, can lead to considerable, irreversible loss of tooth structure. In its advanced stages, when it has progressed to the middle or inner thirds of dentin, the carious lesions may become cavitated. Once a cavity develops, the only resort is to restore it with an artificial material. Intervening when the carious lesion is still in its incipient stages could potentially prolong the life of a tooth. Curodont Repair Fluoride Plus can be used to non-invasively treat early caries (watch areas/white spot lesions) and help arrest progression.
* Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet 2018; 392: 1789–8583
Yes, Curodont Repair Fluoride Plus can be used in patients at high risk for developing caries. However, in such cases, a strict regimen of regular recalls and reinforcement of oral hygiene measures must be adopted.
One application of Curodont Repair Fluoride Plus per lesion may be enough to arrest or regress the early caries. Nevertheless, it can be re-applied during future visits if deemed necessary by the clinician, such as in cases where there is inadequate oral hygiene maintenance by the patient.
No. The use of a rubber dam is not necessary, though it is the clinician’s decision whether to use a rubber dam. Isolation with cotton rolls and a saliva ejector is sufficient.
In many cases, one application of Curodont Repair Fluoride Plus is sufficient to treat one lesion, provided the patient maintains good oral hygiene following application.
If deemed necessary by the clinician, the application may be repeated.
Curodont Repair Fluoride Plus, with 500 PPM of sodium fluoride as the active ingredient, has no reported side effects. It has been used on over 150,000 teeth in the USA since 2019 with no reported adverse events. Regular dental appointments to detect caries in the earliest stages and their non-invasive management using Curodont Repair Fluoride Plus is recommended.
Curodont Repair Fluoride Plus is a proprietary formula that treats early caries by remineralization. Sodium Fluoride is also known to be an effective remineralization agent. The speed with which the caries is arrested or regresses depends on a number of patient behavioral and environmental factors, such as oral hygiene maintenance, quality of saliva, dietary habits, etc. Many patients see arrest or regression after one application.
Curodont Repair Fluoride Plus addresses early caries (watch areas/white spot lesions) non-invasively through remineralization. In this process, the white appearance of the lesions may fade to a significant extent but might not completely disappear. Additionally, Curodont Repair Fluoride Plus is not intended to treat cosmetic white spots.
No. Curodont Repair Fluoride Plus can be used in conjunction with other remineralizing agents, such as fluoride varnish, to optimize remineralization. These agents act as suppliers of calcium, phosphate, and/or fluoride ions which supports the proprietary formula’s treatment of early carious lesions (watch areas/white spot lesions). When using these agents, they must be applied at least 5 minutes after the application of CRFP in-office, or after the appointment, at home.

An ideal complement to Curodont Repair Fluoride Plus is Curodont Protect. This anti-cavity dental gel can be applied once or twice a week on the treated area and on the entire dentition at home.
Immediately after the application of Curodont Repair Fluoride Plus, the patient should refrain from eating or drinking for 30 minutes. Routine oral hygiene measures including brushing with fluoridated toothpaste twice a day must be strictly followed. Additionally, and especially, in cases with early proximal caries, interdental flossing must be performed after meals to ensure the cleanliness of the area. Good oral hygiene maintenance is a pre-requisite for the success of any dental treatment.
Yes, CRFP is a unique treatment that can be used on early caries developing around bonded brackets. Patients undergoing fixed orthodontic treatment are at an increased risk of developing caries, due to difficulty in oral hygiene maintenance. Since the use of CRFP does not require the placement of a rubber dam or any finishing and polishing procedures, it can easily be used around bonded brackets.
The demineralized environment within early carious lesions provides an environment for the CRFP proprietary formula to work. CRFP is not indicated for use in cosmetic white spots or those that have a non-bacterial etiology.
There are several parameters by which one can assess the Curodont Repair Fluoride Plus treatment:
  1. No progression of the carious lesion over time
  2. Reduction in the grade of the carious lesion: As remineralization takes place, the early carious lesion becomes smaller, which can be judged on a radiograph or with diagnostic aids employing transillumination.
  3. Morphological reduction in the size (width) of the white spot lesion.
  4. Reduction in the ‘whiteness’ of the lesion. However the lesion might not completely regain the appearance of sound enamel.
While it does not kill the caries-producing bacteria, CRFP’s proprietary formula helps attract calcium and phosphate found in the saliva to remineralize the early carious lesions. These minerals are delivered to the lesion to help arrest the caries.
CRFP is a treatment for early caries. It works best if it has a demineralized, porous surface to penetrate. Where the tooth is fully intact, the CRFP would not have a surface to penetrate and would wash away. Thus, it is not an appropriate product to use on intact tooth surfaces.
Curodont Protect, an anti-cavity dental gel, would be a product for caries prevention, including for patients at high caries risk.
The waiting time of 5 minutes after the application of CRFP is to ensure that the product diffuses throughout the early carious lesion (watch area/white spot lesion). These 5 minutes can be utilized to provide oral hygiene instructions to the patient. The patient can semi-close the mouth and a saliva ejector may be used to suction out the saliva at regular intervals. The patient must not rinse until the 5 minutes have expired.
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Testimonials

“Now, we have a product that enables early intervention and the remineralization of early caries before a restoration is required.”
Robert Mongrain
Robert MongrainDMD
“Adopting minimally invasive, early interception methods is the future of dentistry and in the best interest of our patients.”
Sarah Eller
Sarah EllerRDH, IPDH
“The really cool part I love about Curodont, it really gives the hygienist a new opportunity and really expands their scope of practice in a way. "
Misty Mattingly
Misty MattinglyRDH
“Join the revolution in dental care, say goodbye to the old ways of fearing the dentist and hello to a brighter healthier smile with vVARDIS Curodont Repair Fluoride Plus.”
Misty Mattingly
Misty MattinglyRDH
“My patients are excited about the idea of no needle or drilling in addition to preventing the long-term maintenance a restoration requires. I am pleased that we’ve been able to educate patients on early caries intervention”
Sarah EllerRDH, IPDH
“Having Curodont Repair Fluoride Plus in my toolkit empowers me to offer more individualized care and better meet the needs of my patients. It expands your options to better serve your patient population and provide comprehensive patient care.”
Jeanette MacLean
“Offering Curodont is only going to help your practice grow, so why would you just watch something in this day and age when you can do something? If we have a treatment option that can help prevent incipient lesions from reaching the point of no return and extend the lifetime of patients’ natural dentition, that is very advantageous”
Jeanette MacLean
“I have been waiting my whole career to become a medical dental doctor, to get to the root cause. This formulation product to allow me to fulfil my career.”
Dr. Robert Mongrain
“I'm just so thankful for products like these, because I can do something instead of just watching and waiting. I can actually do something to help this patient.”
Crystal SpringRDH
“Curodont Repair Fluoride Plus is popular with patients, a large majority of whom have enthusiastically accepted treatment upon learning about the opportunity to address a non-cavitated lesion before it can worsen and possibly lead to invasive restorative treatment. ….. That’s because they like the idea of not having to be drilled on for a restoration."
Dr. William J Moorhead (‘Dr. Checklist’)DMD
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